When do you know that the relationship is over?

It's incredible that as a species we have not unpacked one of the most basic elements of human interaction. The inane and yet incredibly significant question: When do we know that a relationship is over?

This question could apply to many different types of relationships namely business, friendships and more to my point, romantic ones. I find it curious that the intellect arrives at a conclusion much earlier than the heart. The heart, however, has an intelligence all of its own and will have none of it.

The perennial stop starts of relationships can be destructive and strips away at the simplicity inherent to loving. I will suggest that the following points (not exhaustive) are strong indicators that a relationship is over and that an intervention akin to America's introduction to world war 2 is required:
* The level of discourse has reached monosyllabic responses
* Apathy sets in around the things that distresses one or both of the romantic partners
* Greater emotional comfort can be found outside of the relationship than within it
* A lowering of courtesy in engagement
* Self-centred focus of needs
* A lack of delight in the achievements by one or both of the romantic partners
* Where persons outside of the relationship knows more about the feelings of one of the partners than the partner

Isolated incidences of one or more of the above factors should not be construed as evidence of a terminally ill relationship. Collectively, however, the writing is on the proverbial wall.