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Graham Brady, the head of the party committee running the contest, said the party board would meet to discuss confirming May as the winner. He did not say how long that might take.
May, who also supported remaining in the EU, is one of the most experienced ministers in Cameron's Cabinet, serving in the notoriously difficult job of interior minister for six years. If confirmed, the 59-year-old politician could become Britain's prime minister within days. She would be the second woman to hold the job.
Leadsom's announcement came after a weekend uproar over her comments about the role of motherhood in politics. Leadsom at first defended, and then apologized for, an interview in which she said that being a mother "means you have a very real stake in the future of our country." Leadsom has children; May does not.