Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments. ( Archived) (32)

Jun 27, 2020 5:36 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty
tomcattytomcattyCoral Bay, Paphos, Paphos Cyprus368 Threads 6 Polls 6,885 Posts
Embedded image from another site


MILWAUKEE – Startling, never-before-seen images show that the new coronavirus hijacks proteins in our cells to create monstrous tentacles that branch out and may transmit infection to neighboring cells.

The finding, accompanied by evidence of potentially more effective drugs against COVID-19, published Saturday in the journal Cell by an international team of scientists.

Embedded image from another site

By focusing on the fundamental behavior of the virus — how it hijacks key human proteins and uses them to benefit itself and harm us — the team was able to identify a family of existing drugs called kinase inhibitors that appear to offer the most effective treatment yet for COVID-19.

"We've tested a number of these kinase inhibitors and some are better than remdesivir," said Nevan Krogan, one of more than 70 authors of the new paper, and director of the Quantitative Biosciences Institute at the University of California, San Francisco.

Wow, this virus seems to plan it's strategy, how does it do that??????????

While remdesivir has yet to be approved for use against COVID-19, U.S. regulators are allowing "emergency use" of the drug in hospitalized patients.

Krogan said tests of kinase inhibitors showed some, including Gilteritnib and Ralimetinib, required lower concentrations than remdesivir in order to kill off 50% of the virus.

The new study, which involved experiments using cells from humans and others from African green monkeys, shows that the virus known as SARS-CoV-2 is especially adept at disrupting vital communications. These communications take place both within cells and from one cell to another.
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Jun 27, 2020 5:43 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty
tomcattytomcattyCoral Bay, Paphos, Paphos Cyprus368 Threads 6 Polls 6,885 Posts
tomcatty: MILWAUKEE – Startling, never-before-seen images show that the new coronavirus hijacks proteins in our cells to create monstrous tentacles that branch out and may transmit infection to neighboring cells.

The finding, accompanied by evidence of potentially more effective drugs against COVID-19, published Saturday in the journal Cell by an international team of scientists.


By focusing on the fundamental behavior of the virus — how it hijacks key human proteins and uses them to benefit itself and harm us — the team was able to identify a family of existing drugs called kinase inhibitors that appear to offer the most effective treatment yet for COVID-19.

"We've tested a number of these kinase inhibitors and some are better than remdesivir," said Nevan Krogan, one of more than 70 authors of the new paper, and director of the Quantitative Biosciences Institute at the University of California, San Francisco.

Wow, this virus seems to plan it's strategy, how does it do that??????????

While remdesivir has yet to be approved for use against COVID-19, U.S. regulators are allowing "emergency use" of the drug in hospitalized patients.

Krogan said tests of kinase inhibitors showed some, including Gilteritnib and Ralimetinib, required lower concentrations than remdesivir in order to kill off 50% of the virus.

The new study, which involved experiments using cells from humans and others from African green monkeys, shows that the virus known as SARS-CoV-2 is especially adept at disrupting vital communications. These communications take place both within cells and from one cell to another.
Wow it seems to plan it's strategy, how does it do that??????
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Jun 27, 2020 6:11 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty: Wow it seems to plan it's strategy, how does it do that??????
Phone the White House Donald will have the answer.grin

Milwaukee in particular has had an aggressive attack from the virus which seems to be getting worse across America.

Both the U.S. and the U.K. need to get a grip as this is becoming a real problem unless Governments don't step up to the plate and take more control . People need to start acting sensibly too. sigh
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Jun 27, 2020 6:51 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
galrads
galradsgalradsDublin, Ohio USA2,264 Threads 279 Polls 36,283 Posts
Yes, i am so startled. Really startled! Ahhhhhhhhhhhhhhhh beer
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Jun 27, 2020 7:14 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
galrads
galradsgalradsDublin, Ohio USA2,264 Threads 279 Polls 36,283 Posts
laugh
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Jun 27, 2020 7:21 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
bodleing2
bodleing2bodleing2Manchester, Greater Manchester, England UK84 Threads 6,132 Posts
galrads: Yes, i am so startled. Really startled! Ahhhhhhhhhhhhhhhh
But you're American. ..Americans don't do sarcasm.

laugh
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Jun 27, 2020 8:20 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
tomcatty: Wow it seems to plan it's strategy, how does it do that??????
Probably played lots of war games on the Playstation
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Jun 27, 2020 8:23 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty
tomcattytomcattyCoral Bay, Paphos, Paphos Cyprus368 Threads 6 Polls 6,885 Posts
Bnaughty: Probably played lots of war games on the Playstation
Oh by the way thattop picture is of youlaugh laugh laugh laugh
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Jun 27, 2020 9:34 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
tomcatty: Oh by the way thattop picture is of you
You look like the wrong end of a bulldog
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Jun 27, 2020 9:37 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty
tomcattytomcattyCoral Bay, Paphos, Paphos Cyprus368 Threads 6 Polls 6,885 Posts
Bnaughty: You look like the wrong end of a bulldog
Bull dogs don't havea wrong enddunno
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Jun 27, 2020 9:40 AM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
tomcatty: Bull dogs don't havea wrong end
Well okay then, you look like both ends
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Jun 27, 2020 1:26 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
tomcatty: No problem plenty for everyone
You could fertilize the galaxy with the stuff that you spew
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Jun 27, 2020 1:40 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty
tomcattytomcattyCoral Bay, Paphos, Paphos Cyprus368 Threads 6 Polls 6,885 Posts
Bnaughty: You could fertilize the galaxy with the stuff that you spew
Makes me sound quite potentlaugh laugh laugh
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Jun 27, 2020 1:43 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
tomcatty: Makes me sound quite potent
Indeed
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Jun 27, 2020 1:45 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Lasagna
LasagnaLasagnaBuenos Aires, Argentina10 Threads 191 Posts
That picture is CGI professor
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Jun 27, 2020 1:51 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
tomcatty
tomcattytomcattyCoral Bay, Paphos, Paphos Cyprus368 Threads 6 Polls 6,885 Posts
Lasagna: That picture is CGI
Not at all it wastaken with an electron microscope
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Jun 27, 2020 1:51 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
Lasagna: That picture is CGI
Have you got any good pics?
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Jun 27, 2020 1:58 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
galrads
galradsgalradsDublin, Ohio USA2,264 Threads 279 Polls 36,283 Posts
Bnaughty: You could fertilize the galaxy with the stuff that you spew
You could do that to infinity and beyond. rolling on the floor laughing
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Jun 27, 2020 2:02 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
Bnaughty
BnaughtyBnaughtyMálaga, Andalusia Spain43 Threads 2 Polls 4,685 Posts
galrads: You could do that to infinity and beyond.
You could do that and fill in all the black holes
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Jun 27, 2020 2:19 PM CST Startling images reveal coronavirus forming tentacles in cells. It may help identify new treatments.
galrads
galradsgalradsDublin, Ohio USA2,264 Threads 279 Polls 36,283 Posts
Bnaughty: You could do that and fill in all the black holes
You’ve been barking at the moon too long if you believe that. grin
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