Why COVID-19 is much worse than flu ( Archived) (4)

Oct 3, 2021 6:35 AM CST Why COVID-19 is much worse than flu
Tulefell
TulefellTulefellGothenburg, Vastra Gotaland Sweden104 Threads 5 Polls 3,306 Posts
Information for the interested. I chose a few paragraphs, you can read the whole article here:



October 1, 2021
Kevin Kavanagh, MD

Unlike influenza, SARS-CoV-2 uses ACE2 receptors to infiltrate cells. Similar to HIV, SARS-CoV-2 can silently spread throughout the host’s body and attack almost every organ.

Medicine appears to have largely bought into the SARS-CoV-2 seasonal influenza analogy. Everything appears to be focused on pulmonary disease. Fringe coronavirus deniers started the narrative that COVID-19 was like the flu. This disinformation narrative has taken hold and has even affected decision making of prominent scientific committees, where disease severity is increasingly defined as a hospitalization (most commonly due to pulmonary distress), rather than the potential chronic and long-term disabling sequelae.

(...)

COVID-19 has a number of presentations and pulmonary is just one. More than anything else, the receptor used for attachment determines the behavior of any virus, along with what organs and even species it can infect.

Human rhinoviruses, the most common cause of a cold, uses the ICAM-1 (intercellular adhesion molecule-1) receptor to enter cells. This receptor allows the virus to replicate in sinus tissues but not to a variety of other tissues. The influenza virus attaches to cells via sialic acid receptors, (...) The influenza virus primarily targets a patient’s lungs, but then the patient’s immune response can also produce a myriad of system symptoms from loss of appetite and myalgias. HIV uses the CD4 receptor residing on Lymphocytes. HIV is initially asymptomatic, and the initial stages of disease can easily be classified as “mild”, a disease which, if left untreated, almost uniformly turns aggressive and fatal over the course of 8 to 10 years.

In the case of SARS-CoV-2, the virus which causes COVID-19, the ACE2 receptor is used for viral entry into the cells. The ACE2 receptor is entirely different to that used by the rhinovirus and seasonal flu. (...) This receptor is present throughout the body, not just the lungs.

(...)
Thus, there are multiple presentations of SARS-CoV-2 including pulmonary, cardiac, gastrointestinal (GI), and central nervous system (CNS). (...)
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Oct 13, 2021 2:29 AM CST Why COVID-19 is much worse than flu
ChesneyChrist
ChesneyChristChesneyChristManchester, Greater Manchester, England UK7,144 Posts
The timing. In the west its like finding out a partner you were about to leave has cancer. Just when we needed loyalty, commitment and endurance we have malcontents and flakes
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Oct 13, 2021 9:00 AM CST Why COVID-19 is much worse than flu
Selenite
SeleniteSeleniteMálaga, Andalusia Spain59 Threads 1 Polls 6,299 Posts
Tulefell: Information for the interested. I chose a few paragraphs, you can read the whole article here:



October 1, 2021
Kevin Kavanagh, MD

Unlike influenza, SARS-CoV-2 uses ACE2 receptors to infiltrate cells. Similar to HIV, SARS-CoV-2 can silently spread throughout the host’s body and attack almost every organ.

Medicine appears to have largely bought into the SARS-CoV-2 seasonal influenza analogy. Everything appears to be focused on pulmonary disease. Fringe coronavirus deniers started the narrative that COVID-19 was like the flu. This disinformation narrative has taken hold and has even affected decision making of prominent scientific committees, where disease severity is increasingly defined as a hospitalization (most commonly due to pulmonary distress), rather than the potential chronic and long-term disabling sequelae.

(...)

COVID-19 has a number of presentations and pulmonary is just one. More than anything else, the receptor used for attachment determines the behavior of any virus, along with what organs and even species it can infect.

Human rhinoviruses, the most common cause of a cold, uses the ICAM-1 (intercellular adhesion molecule-1) receptor to enter cells. This receptor allows the virus to replicate in sinus tissues but not to a variety of other tissues. The influenza virus attaches to cells via sialic acid receptors, (...) The influenza virus primarily targets a patient’s lungs, but then the patient’s immune response can also produce a myriad of system symptoms from loss of appetite and myalgias. HIV uses the CD4 receptor residing on Lymphocytes. HIV is initially asymptomatic, and the initial stages of disease can easily be classified as “mild”, a disease which, if left untreated, almost uniformly turns aggressive and fatal over the course of 8 to 10 years.

In the case of SARS-CoV-2, the virus which causes COVID-19, the ACE2 receptor is used for viral entry into the cells. The ACE2 receptor is entirely different to that used by the rhinovirus and seasonal flu. (...) This receptor is present throughout the body, not just the lungs.

(...)
Thus, there are multiple presentations of SARS-CoV-2 including pulmonary, cardiac, gastrointestinal (GI), and central nervous system (CNS). (...)
Unlike flu' and HIV which eventually present some symptoms, with Covid 19 one appears to be able to test positive multiple times and yet present no symptoms whatso ever. wow
It is also possible to spent close time with someone testing positive to covid 19 and yet not "catch it"...
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Oct 13, 2021 9:06 AM CST Why COVID-19 is much worse than flu
mikey4691
mikey4691mikey4691Knoxville, Tennessee USA8 Threads 6,868 Posts
The poor old flu got kicked to the curb when Covid showed up... dunno
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