Not quick because of the testing but tests are being run on
THOUSANDS of people, not handfuls of brave volunteers, which does mean results far, far sooner than new vaccines, and look at the results already ... That said, the WHO has cautioned (April 11, 2020) there is no guaranteed link between the BCG vaccine and Covid19 prevention. Their concern is obviously to ensure there is no shortage of the vaccine in the countries where it is essential, because of a sudden rush of demand. Fair comment. However they are closely monitoring several trials but don’t expect to be able to get your shot – or have it ruled out – in a week or so.
There is however definite interest and some huge studies / trials are in progress.
Published April 6, 2020 -
“While we expected to see a protective effect of BCG, the magnitude of the difference (almost 10 fold) in incidence and mortality (of Covid-19) between countries with and without a BCG vaccination program was pleasantly surprising,” said Dr. Ashish Kamat, a co-author of the paper and professor of Urologic Oncology (Surgery) and cancer research at MD Anderson Cancer Center in Houston, Texas.
The study looked at Covid-19 instances and mortality for 15 days between 9 and 24 March in 178 countries and concluded that “incidence of Covid-19 was
38.4 per million in countries with BCG vaccination compared to
358.4 per million in the absence of such a program. The death rate was
4.28/million in countries with BCG programs compared to
40/million in countries without such a program.” Out of the 178 countries studied, 21 had no vaccination program, while the status was unclear in 26 countries. The latter group was treated as not having a policy for the purpose of this study.
The link for the above excerpts is
Published April 23, 2020
The WHO is closely monitoring the progression of two clinical trials investigating the effect of BCG vaccination in healthcare workers
- Phase III BRACE clinical trial, an Australian study sponsored by the Murdoch Children’s Research Institute in collaboration with The Royal Children’s Hospital (
4000 participants)
- Phase III BCG-CORONA trial, a Dutch study sponsored by the University Medical Center Uterecht in collaboration with Radbound University (
1500 participants)
Baylor College of Medicine and Ain Shams University are both conducting similar trials in which the patient population consists of health workers, and the trials are under Phase IV and Phase III level of development, respectively. One will last 9 months and the other 6 months. Number of participants not advised.
Two more trials have recently been registered. A Phase IV study in the Netherlands aims to test an elder patient cohort, where participants are ages 60 years or older. (
1600 participants, 6 months)
A Phase II trial located in Egypt sponsored by Assiut University will assess the severity of Covid-19-positive patients ages 12–80 years previously vaccinated with a BCG vaccine to assess if the vaccine decreases the impact but will only use
100 subjects. Duration will be 2.2 months.
Link to the above excerpts is
I chose to start a new blog rather than add to my original blog about BCG because there was so much new data - also chose not to add to another blog about vaccines for the same reason.