More science?.....
...The Broken Heart...Pins in Voodoo dolls, mal de ojo, and other phenomena. Widowhood heart break syndrome. (Trump Derangement-Hilary Deficit Syndrome?) But I digress. Well, most cardiologists aren't convinced. But there is evidence for such. For starters, the poets write, that the seat of much emotion, or at least the destination of these feelings, is some part of the heart. And after all, the organ is chock full of all sorts of important neurological (stretch-volume), and hormonal circuits, long know by science. In some branches of acupuncture, heart meridians are important for emotions, although others, such as liver/lung, may be more so. Everything from factors that measure and respond to blood pressure, etc., and is one important target of output from the Vagus nerve, also known as the wanderer, for all the places it travels, after leaving midbrain regions. Simple surface skin massage of branches of the Vagus can even break some abnormal heart rates. Heart transplant patients sometime claim newer emotions, not unlike the ones who donate the organ. When we experience a severe loss, often in the family, with pets, or in love, while the range of resilience is quite broad here, a small percentage of people can be severely affected, by much more than mere emotional loss and grief. Similar stories during great financial loss, as in the depression. The technical names for this vary, but seem to focus on heart rhythms, although other mechanisms may be involved. Of course, apart from suicide, the two main mechanisms seem to involve changes in heart function that normally resolve in most more resilient folks, but remain longer term in these victims. I've experienced such with such losses a few times in my otherwise lady killer life. My own vote is that the syndrome might be real. Perhaps only a bit less so than that monster, TD-HDS.
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And depression can result from being sick or vice versa. The mind lives in the body. Again no surprise.